The PerMè 360 Test helps you understand if you are consuming too much sugar or specific foods by measuring the inflammation in your body, interpreting any genetic predisposition to the most significant metabolic diseases, and assessing your true biological age. GEK Lab’s doctors and specialists, experts in precision medicine, based on the results, will suggest a personalized nutritional and integrative path for you.
Also available at GEK Lab locations
What do I get from my PerMè 360 Test?
- A medical diagnosis based on the interpretation of laboratory data.
- Measurement of your inflammatory levels (BAFF and PAF), also related to your daily diet (food-related inflammation).
- Identification of your Personal Food Profile, which allows for nutritional personalization through a rotation diet of the Major Food Groups.
- Measurement of your glycation and inflammation levels from sugars through the analysis of two molecules: glycated albumin and methylglyoxal, which also highlight the potentially harmful effects of all types of sugars and polyols (such as fructose, glucose, maltose, sorbitol, galactose, and others) and alcohol.
- Evaluation of any genetic polymorphisms that characterize a greater personal susceptibility to the development of diabetes, obesity, liver steatosis, and autoimmune diseases.
- Your BioAge: an interpretation of your biological age, linked to the length of telomeric DNA, in comparison to your chronological age.
- 6 months of free access to the MyGEK Lab service, a scientific counseling service that provides a collection of frequently asked questions and direct contact with a team of nutritionists.
- Personalized integrative advice: what are the active principles useful to counteract the inflammation levels found by the test.
The PerMè 360 Test addresses the following aspects
FAQ
Nutrition can play a pivotal role in managing workload and chronic stress. Chronic stress has been shown to accelerate cellular aging, as indicated by biological age measurements in the PerMè 360 Test. This comprehensive test offers insights into health status and recommends specific stress management strategies, nutraceutical support, and advice on physical activity. Maintaining a balanced diet, particularly focusing on reducing inflammation from sugars and processed foods, is crucial for absorbing essential nutrients necessary to tackle daily challenges, sustain concentration, and preserve cognitive function.
The PerMè 360 Test is extremely beneficial for athletes. In sports, nutrition is crucial for achieving optimal performance and maintaining proper health. The PerMè 360 Test focuses on aspects such as glycation, a biochemical process that can disrupt the proper functioning of muscle cells, and chronic inflammation resulting from a repetitive diet, both of which can compromise muscle elasticity, cellular regeneration, and the body’s ability to produce energy, thus affecting athletic performance. The test provides a detailed assessment of relevant markers, allowing for the customization of a targeted nutritional protocol. This can maximize athletic performance, improve muscle strength, endurance, and speed up recovery after training. In summary, the PerMè 360 Test is a valuable tool for athletes seeking to optimize their nutrition to reach higher levels of performance.
Bloating, especially upon waking up and involving hands and face, can be associated with water retention issues and, consequently, inflammation. Very often, a diet that is excessively repetitive over time and too rich in sugars (including fruits), alcohol, and any sweeteners is one of the main causes of inflammation. Measuring low-grade systemic inflammation levels through analytes such as BAFF and PAF, along with identifying the Major Food Groups consumed in excess and values of Glycated Albumin and Methylglyoxal related to sugar damage, allows for adopting a dietary strategy based on rotation and sensible insertion of sweets and related substances, thus reducing inflammation. Inflammation is a condition that tends to promote fluid retention and weight gain; controlling these processes allows for expelling excess fluids and reducing the annoying symptom of bloating.
The PerMè 360 Test is recommended during pregnancy and provides valuable information on inflammatory responses. Individual food rotation allows for maintaining a varied diet without excluding specific foods. During pregnancy, it is essential to pay attention to the quality of food and balance carbohydrates and proteins as indicated in the medical report. Controlling food-related inflammation can help prevent complications such as gestational diabetes and reduce the physiological inflammatory responses of this delicate period.
Hypertension, often present even in young individuals, benefits from controlling food-related inflammation. The PerMè 360 Test identifies the personal dietary profile, allowing the creation of a personalized weekly food rotation plan that helps reduce inflammation and the production of free radicals, particularly influential in the cardiovascular system. Additionally, excessive consumption of sugars, refined carbohydrates, sweeteners, and alcohol contributes to damaging the inner lining of blood vessels, promoting the development of hypertension.
Frequently, a weakened immune system is associated with low-grade chronic inflammation, caused by unbalanced diets and unhealthy lifestyles. The PerMè 360 Test is a valuable tool for controlling inflammation, especially that derived from glycation and food. By analyzing the results of this test, specific nutritional strategies can be identified to counteract inflammation and provide the body with the necessary nutrients for a strong and responsive immune system.
The excessive proliferation of candida can lead to the infection known as candidiasis. Changes in intestinal microflora, often resulting from dietary habits and lifestyles, are among the main causes of candidiasis. The presence of food-related inflammation and excessive intake of sugars, alcohol, and sweeteners can lead to an alteration of the bacterial flora. The PerMè 360 Test evaluates Food Groups that trigger inflammatory responses and levels of sugar-related inflammation, allowing for the customization of the diet to facilitate the restoration of oral, intestinal, and vaginal bacterial flora, reducing inflammation and promoting overall well-being, without excessive and counterproductive restrictions.
Yes, the PerMè 360 Test can provide valuable information for those suffering from thyroid disorders. Variations in thyroid values involve inflammatory, metabolic, environmental, and genetic aspects. Metabolic alterations and thyroid dysfunction can also depend on excessive intake of simple sugars, sweeteners, and alcohol. The PerMè 360 Test, through the measurement of the cytokine BAFF, correlated with autoimmunity, and the evaluation of the respective genetic predisposition, in addition to the analysis of early sugar damage, provides crucial information for adopting a balanced and personalized diet, fundamental for the correct thyroid balance. Personalizing the diet helps reduce inflammatory stimuli and improve thyroid function.
Simultaneously assessing inflammation from sugars and from food is useful because these inflammatory forms act synergistically, amplifying each other. Clinical experience shows that disorders such as chronic fatigue, difficulty in losing weight, gastrointestinal problems, and skin issues benefit from a coordinated intervention on diet and sugars. The PerMè 360 Test provides a comprehensive evaluation of inflammation levels related to food and early sugar-related damage.
It is scientifically known that many skin reactions are correlated with chronic inflammatory conditions, often induced by food. The PerMè 360 Test provides an accurate assessment of the degree of inflammation in the body, including that caused by glycation. Foods, if consumed excessively, can trigger inflammatory responses that mimic allergic reactions, even in the absence of confirmed allergies. Glycation, a phenomenon in which sugar alters the function of the body’s proteins, amplifies such issues. The strategies indicated in the PerMè 360 medical report can lead to the disappearance of persistent skin symptoms, which sometimes do not adequately respond to treatment with antihistamines and topical creams.
The PerMè 360 Test analyzes specific markers to measure inflammation in the body, often at the root of overweight conditions. Markers such as BAFF and Methylglyoxal, which increase in response to high or repeated intake of foods and excessive consumption of sugars, sweeteners, and alcohol, cause insulin resistance leading to fat accumulation. By reducing inflammation through the modulation of these molecules, it’s possible to address insulin resistance and consequently metabolism, promoting weight loss. It’s important to emphasize that the PerMè 360 Test offers an approach without elimination diets, which can be counterproductive both for the body and psychologically. Instead, by focusing on reducing inflammation, the test provides specific indications to adopt targeted nutritional changes, supporting the fight against being overweight more effectively and sustainably.
Yes, the health of nails and hair is strongly influenced by diet. Micronutrients and macronutrients such as zinc, selenium, vitamins, and amino acids are essential for their growth and regeneration. However, chronic inflammatory conditions, often linked to diet, can compromise the optimal absorption of these nutrients, causing issues like hair loss and weakening of nails. The PerMè 360 Test provides a comprehensive analysis of food-related inflammation, allowing for the identification and mitigation of these issues through targeted nutritional changes.
The PerMè 360 Test can be of great help during menopause to understand how to adapt nutrition to the body’s new needs. During menopause, rooted dietary habits can begin to negatively impact energy, mood, metabolism, leading to weight gain, chronic fatigue, sleep difficulties, and irritability. Menopause brings significant physiological changes, especially hormonal ones, sometimes linked to inflammatory processes. This inflammation can be further exacerbated by poor dietary habits and excessive sedentary behavior. The PerMè 360 Test allows for the customization of a dietary plan tailored to these changes, providing specific and precise guidance to follow throughout the week. This way, it’s possible to positively impact body composition, energy levels, emotional well-being, improving the quality of life during this transition period.
In the presence of osteoporosis, proper nutrition plays a fundamental role in maintaining bone health and preventing further demineralization. Inflammation can compromise the absorption of crucial nutrients for bone metabolism, such as calcium, zinc, selenium, and vitamin D, increasing the risk of fractures. One of the substances that the PerMè 360 Test analyzes is BAFF, an inflammatory substance that, along with its multiple activities, has the ability to “dissolve bone” (stimulate osteoclastic activity). Improving nutrition in a personalized way and consequently reducing inflammation helps maintain bone health. The personalized nutritional protocol also improves intestinal absorption and therefore the absorption of important micronutrients such as calcium and vitamin D, which are essential for bone remineralization. Therefore, the nutritional intervention of the PerMè 360 Test supports bone health and reduces the risk of complications related to osteoporosis.
The presence of chronic fatigue and drowsiness may be correlated with a strong inflammatory component in the body. This chronic inflammatory state can compromise the absorption of nutrients such as proteins, B vitamins, zinc, copper, and selenium, essential for maintaining optimal energy levels. It is important to understand which foods have been consumed excessively, contributing to the inflammatory condition. Additionally, inflammation caused by sugars and metabolically related substances (such as alcohol, fructose, and sweeteners) can directly affect adenosine triphosphate (ATP) production, the main cellular energy source, negatively impacting overall energy status. Glycation, a sugar-related phenomenon, can also affect nerve function, contributing to a condition known as “brain fog” or mental fog. A synergistic approach to addressing inflammatory forms from sugars and foods can be achieved through the PerMè 360 Test. This test helps identify foods that may contribute to the inflammatory condition, improving the absorption of essential nutrients for energy production and directly acting on cellular energy production, helping to counteract mental and physical fatigue.
Gum problems and bad breath can be related to chronic inflammatory conditions. Excessive consumption of foods can contribute to gastroesophageal disorders that can cause halitosis, while an excess of sugars can promote the formation of cavities or even periodontitis that compromise oral health. The PerMè Test identifies food groups that may support these and other inflammatory conditions. Identifying and moderating the consumption of specific foods while maintaining a healthy and varied diet helps improve gum health and reduce associated bad breath.
Telomeres are the ends of chromosomes and they serve the function of protecting DNA from random damage during cell replication. Physiologically, telomeres shorten over time; however, chronic stress, influenced by lifestyle and imbalanced nutrition, accelerates telomere shortening. This results in telomeres becoming less effective in carrying out their protective function, leading to premature aging and an increased risk of developing conditions such as diabetes.
Knowing one’s biological age is important because it provides a more accurate assessment of health status and disease risk compared to chronological age. While chronological age simply represents the number of years since birth, biological age reflects the physical and physiological state of the body, including aging processes and overall level of well-being. Knowing one’s biological age allows individuals to adopt more targeted preventive measures, adjusting their lifestyle, diet, and physical activity to maintain and improve long-term health.
Telomere shortening is a physiological process that occurs in our bodies as we age. However, this process can be accelerated by various factors: the presence of chronic stress, persistent inflammation, and an inadequate lifestyle, including unhealthy eating habits. Certainly, chronic inflammation and oxidative stress related to glycation processes and an imbalanced diet can significantly contribute to the speed of telomere shortening. Consequently, progressive telomere shortening has been associated with cellular aging and increased susceptibility to age-related diseases. Maintaining a healthy lifestyle, managing stress, and adopting a balanced and personalized diet are essential for protecting telomeres and preserving cellular health and overall organism health over time.
BioAge, resulting from the interpolation of scientific, demographic, and biological data, estimates the biological and cellular aging of the body, differing from chronological age, which simply counts the years since birth. Cellular aging is a natural process, but various lifestyle factors such as balanced diet, physical activity, adequate rest, and avoiding harmful behaviors can positively influence BioAge. The goal is to maintain a consistent or younger biological age compared to chronological age through healthy lifestyle choices and habits. Understanding this difference can guide lifestyle changes and suggest personalized approaches to slow down cellular aging.
BioAge is assessed by measuring the average length of telomeric DNA in leukocytes. Telomeres are the terminal part of each chromosome that protects their ends from shortening due to time, aging, and oxidation effects. Telomere length in leukocytes (LTL) is determined by comparing these chromosomal segments with a gene of known length. As highlighted by an increasing number of scientific studies, telomere shortening is a physiological process; however, if accelerated, it can be a sign of premature cellular aging. The test provides the patient with a synthetic interpretative index, BioAge, calculated by interpolating the patient’s demographic and biological data with a reference statistical sample.
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